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Home » Medications » Naproxen 500 mg Tbl 20 Stk

Naproxen 500 mg Tbl 20 Stk

5α-reductase inhibitor for enlarged prostate

Description

Generic Name: Naproxen
Brand Name: Aleve, Naprosyn, Anaprox
Drug Class: NSAID


This is a prescription medicine, which requires a valid prescription!

Indications

  • Pain relief: Mild to moderate pain (e.g. musculoskeletal, dental, back pain)
  • Inflammation: Arthritis (osteoarthritis, rheumatoid arthritis), bursitis, tendinitis
  • Dysmenorrhea: Menstrual cramps
  • Fever reduction (less common at 500 mg dose)
Mechanism of Action
  • Inhibits cyclooxygenase (COX-1 and COX-2) enzymes
  • Reduces prostaglandin synthesis → decreases inflammation, pain, and fever
  • Longer half-life than ibuprofen → allows for twice-daily dosing
Dosage and Administration
  • Form: Oral tablet, 500 mg
  • Typical Dose:
    • Initial: 500 mg orally, followed by 250 mg every 6–8 hours as needed
    • Maximum: 1,000–1,250 mg/day (depending on indication and duration)
  • Should be taken with food or milk to minimize gastrointestinal upset
  • Use lowest effective dose for shortest possible duration
Side Effects
  • Common:
    • Gastrointestinal upset (nausea, heartburn)
    • Headache
    • Dizziness
    • Edema (fluid retention)
  • Less Common:
    • Elevated liver enzymes
    • Skin rash
    • Ringing in the ears (tinnitus)
  • Serious (Rare):
    • GI bleeding, ulcers, or perforation (risk increases with age, alcohol, other NSAIDs)
    • Cardiovascular events (MI, stroke — especially with prolonged use)
    • Kidney dysfunction
    • Severe allergic reactions (anaphylaxis, Stevens-Johnson syndrome)
Contraindications
  • Known hypersensitivity to naproxen or other NSAIDs
  • History of asthma, urticaria, or allergic reactions after NSAID use
  • Active GI bleeding or peptic ulcer
  • Severe heart failure
  • Advanced renal or hepatic disease

Information

Warnings and Precautions

  • Use with caution in patients with cardiovascular risk factors
  • Avoid in late pregnancy (≥30 weeks gestation — risk of fetal ductus arteriosus closure)
  • Monitor renal function during prolonged use
  • May mask signs of infection or fever

Drug Interactions

  • Anticoagulants (e.g., warfarin): Increased bleeding risk
  • Other NSAIDs or corticosteroids: Increased GI toxicity
  • ACE inhibitors, diuretics: May reduce antihypertensive effect and harm kidneys
  • SSRIs: Additive risk of GI bleeding
  • Lithium: Naproxen may increase lithium levels

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Terms & Conditions

Direct Enquiries
For any inquiries, please feel free to contact us directly via email at the link below.
pharmacy@doctorworld.eu

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