Skip to content
Home » Medications » Valaciclovir 500 mg Tbl 10 Stk

Valaciclovir 500 mg Tbl 10 Stk

Oral antiviral for herpes infections

Description

Generic Name: Valaciclovir (or Valacyclovir)
Brand Name: Valtrex
Drug Class: Antiviral (Nucleoside analog DNA polymerase inhibitor)


This is a prescription medicine, which requires a valid prescription!

Indications

  • Herpes Zoster (shingles)
  • Genital Herpes (initial and recurrent episodes)
  • Herpes Labialis (cold sores)
  • Suppression of recurrent genital herpes
  • Prevention and treatment of cytomegalovirus (CMV) in transplant recipients (off-label in some regions)
Mechanism of Action
  • Valaciclovir is a prodrug of acyclovir
  • Rapidly converted to acyclovir in the body
  • Inhibits viral DNA synthesis by competing with deoxyguanosine triphosphate
  • Effective primarily against HSV-1, HSV-2, VZV, and to a lesser extent, CMV and EBV
Dosage and Administration
  • Form: Oral tablet, 500 mg
  • Typical Adult Dosing:
    • Genital Herpes (initial): 500 mg twice daily for 7–10 days
    • Genital Herpes (recurrent): 500 mg twice daily for 3 days
    • Suppressive Therapy: 500 mg once daily
    • Herpes Zoster: 1,000 mg three times daily for 7 days
    • Cold Sores: 2,000 mg every 12 hours for 1 day
  • Take with or without food
  • Dose adjustment required in renal impairment
Side Effects
  • Common:
    • Headache
    • Nausea
    • Abdominal pain
    • Dizziness
  • Less Common:
    • Rash
    • Fatigue
    • Elevated liver enzymes
  • Serious (Rare):
    • Thrombotic thrombocytopenic purpura (TTP) / Hemolytic uremic syndrome (HUS) – especially in immunocompromised patients
    • Acute kidney injury (more likely with dehydration or high doses)
    • Neurotoxicity (e.g., agitation, hallucinations, confusion) – rare and usually reversible, more common in elderly or renally impaired
Contraindications
  • Hypersensitivity to valaciclovir, acyclovir, or any component of the formulation

Information

Warnings and Precautions

  • Use with caution in patients with renal impairment; adjust dosage
  • Ensure adequate hydration to prevent renal toxicity
  • Use during pregnancy only if benefits outweigh potential risks
  • Safe during breastfeeding in most cases, though monitoring is advised

Drug Interactions

  • Nephrotoxic drugs (e.g., cyclosporine, aminoglycosides): increased risk of renal toxicity
  • Probenecid: may increase plasma concentration of acyclovir
  • Cimetidine: can reduce acyclovir clearance slightly

Request Now

Please enable JavaScript in your browser to complete this form.
Terms & Conditions

Direct Enquiries
For any inquiries, please feel free to contact us directly via email at the link below.
pharmacy@doctorworld.eu

DISCLAIMER

PLEASE AVOID SELF-DIAGNOSIS AND SELF-MEDICATION!

Our website content is posted for informational purposes only. It is not intended to be used for primary diagnoses-making and should not replace a consultation with a professional health care provider. If you have any health issues or complaints, please consult your primary physician.

Health care data provided for informational purposes is not an alternative to an in-person physician consultation.